Mehdi Raadabadi, Rajabali Daroudi, Farzan Madadizadeh, Amirreza Veisi, Sara Emamgholipour, Jamil Sadeghifar,
Volume 7, Issue 2 (Summer 2024)
Abstract
Introduction: As the EQ-5D questionnaire may miss some dimensions of health and has limitations in utility measurement, adding new dimensions to EQ-5D may improve the validity and sensitivity of the measure. The present study was carried out as a systematic review of studies on adding new dimensions to the EQ-5D questionnaire.
Methods: This study was designed as a systematic review. Electronic databases such as Embase, PubMed, ISI/Web of Science and Scopus and two targeted website were mined from inception up to 30st September 2020. General description, version of the EQ-5D, method for valuing, types of bolt-on dimensions, approach for identification of bolt-on dimensions and effect on utilities measurement were extracted. Two authors reviewed the articles independently.
Results: 23 studies were included that eight articles studied only cognitive, four studies only vision, three studies only sleep and in two studies, skin problems were added to EQ-5D questionnaire. The majority of studies were conducted with a three-level scale questionnaire (EQ-5D-3L) and VAS Valuation method (n=11).
Conclusion: Adding bolt-on in some dimensions could change the utility measurement specially in cognitive, vision and respiratory dimensions. Comparison of HRQoL showed significant difference in health states for EQ-5D and EQ-5D+Bolt-on dimensions. EQ-VAS has been reduced with the addition of new dimensions. The results of the studies indicate an enhance in the HRQoL by adding the dimension to the EQ-5D, although the inconsistency between some studies can be related to the valuation techniques, the dimension added and the study conditions.
